What is Premarin Vaginal Cream
Premarin Vaginal Cream is used to treat atrophic vaginitis, a condition caused by low estrogen levels. Atrophic vaginitis can lead to vaginal dryness, irritation, itching, and pain during intercourse. Premarin Vaginal Cream replenishes estrogen locally and helps restore moisture, thickness, and elasticity of vaginal tissues.Premarin Vaginal Cream should be used exactly as prescribed by your doctor. It is applied inside the vagina using the applicator provided, usually at bedtime. For best results, continue using the medicine for the full duration prescribed, even if symptoms improve earlier. Staying hydrated, maintaining good vaginal hygiene, and avoiding irritants like scented soaps or douches can further help relieve symptoms and support treatment effectiveness.
How work of Premarin Vaginal Cream
Common side effects include headache, nausea, vomiting, and vaginal irritation, burning, itching, or discharge. These symptoms are usually temporary and improve as the body adjusts to the medication. If irritation persists or worsens, consult your doctor. If you experience unusual symptoms or signs of an allergic reaction, such as severe itching, swelling, or trouble breathing, seek medical attention immediately.Before using Premarin Vaginal Cream, inform your doctor if you have a history of breast cancer, uterine cancer, blood clots, liver disease, or unexplained vaginal bleeding, as estrogen therapy may not be suitable for you. Avoid using Premarin Vaginal Cream if you are pregnant or breastfeeding. Consider regular medical check-ups, as that will help monitor your response to treatment and ensure safe use.
Benefits of Premarin Vaginal Cream
In Treatment of Hormone replacement therapy
Atrophic vaginitis is a condition caused by low estrogen levels, leading to vaginal dryness, irritation, and thinning of the vaginal walls. Premarin Vaginal Cream helps restore moisture and elasticity, relieving symptoms like pain during intercourse (dyspareunia) and severe vaginal dryness and shrinking of the tissues (kraurosis vulvae). Regular use can improve overall vaginal health, making daily activities and intimacy more comfortable.
Side effects of Premarin Vaginal Cream
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Premarin
- Headache
- Breast pain
- Irregular vaginal bleeding
- Vaginal spotting
- Abnormal vaginal bleeding
- Abdominal cramp
- Bloating
- Nausea
- Vomiting
- Hair loss
- Edema (swelling)
- Vaginal yeast infection
- Application site reactions (burning, irritation, itching and redness)
Quick tips
- Premarin Vaginal Cream can be applied to the external vaginal area or inserted into the vagina using the applicator provided.
- It does not expose the rest of your body to the medicine, thereby avoiding side effects that happen more often with pills.
- Do not have sex right after using Premarin Vaginal Cream, as some of the medicine can be absorbed into your partner’s skin.
- Inform your doctor if you experience any vaginal bleeding or spotting, abnormal vaginal discharge, or vaginal discomfort while using Premarin Vaginal Cream.
- Do not use Premarin Vaginal Cream if you are pregnant or breastfeeding or have active or chronic liver dysfunction or disease.








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